1, 2, 4-Triazole Scafolds : Recent Advances and Pharmacological Applications

Library 1 H - 1 , 2 , 4 , - Triazole Having Significant Pharmacological Activities

1 Recent Advances on Surface Modification of 2 Halloysite Nanotubes for Multifunctional 3 Applications 4

Halloysite nanotubes (HNTs) are natural occurring mineral clay nanotubes that have 11 excellent potential application in different fields. However, HNTs are affected by size, surface 12 electron and hydrogen bond formation on the surface which lead to weak affinity and reunion at 13 certain extent. It is very significant to modify the HNTs’ surface to expand its applications. In this 14 review,...

Green synthesis and evaluation of 5-(4-aminophenyl)-4-aryl-4H-1, 2, 4-triazole-3-thiol derivatives

The green synthesis of 5-(4-aminophenyl)-4-aryl-4H-1,2,4-triazole-3-thiol was achieved in four steps, In first step, 4-amino benzoic acid refluxed in ethanol along with catalyst Conc. Sulphuric acid to produce ethyl-4-amino benzoate I. Further compound I refluxed with hydrazine hydrate in ethanol to produce 4-amino benzohydrazide II. Compound II refluxed in ethanolic potassium hydroxide with ca...

Recent advances in pharmacological neuroprotection

Treatment of brain ischaemic remains a challenging issue. During the last decade there has been much interest in the development of drugs with signifi cant neuroprotective effects against ischaemic injury in stroke patients. However, clinical trials have been disappointing as, so far, they all have failed to provide evidence for neuroprotection. Several reasons including lack of convincing expe...

1-[2-(4-Bromo­benz­yloxy)-2-phenyl­ethyl]-1H-1,2,4-triazole

In the mol-ecule of the title compound, C(17)H(16)BrN(3)O, the triazole ring is oriented at dihedral angles of 6.14 (9)° and 82.08 (9)°, respectively, with respect to the phenyl and bromo-benzene rings. The dihedral angle between the bromo-benzene and phenyl rings is 87.28 (7)°. The intra-molecular C-H⋯O hydrogen bond results in the formation of a planar five-membered ring, which is oriented at...